InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SEC61G

Summary

InnateDB Protein

IDBP-375586.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEC61G

Protein Name

Sec61 gamma subunit

Synonyms

SSS1;

Species

Homo sapiens

Ensembl Protein

ENSP00000409884

InnateDB Gene

IDBG-16894 (SEC61G)

Protein Structure

UniProt Annotation

Function

Necessary for protein translocation in the endoplasmic reticulum. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008565	protein transporter activity
GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity

Biological Process

GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0006412	translation
GO:0006605	protein targeting
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0006886	intracellular protein transport
GO:0010467	gene expression
GO:0015031	protein transport
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0044267	cellular protein metabolic process
GO:0045047	protein targeting to ER
GO:0071806	protein transmembrane transport

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit
IPR008158 Protein translocase SEC61 complex, gamma subunit
IPR023391 Protein translocase SecE domain

PFAM

PF00584

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P60059

PhosphoSite