Version 5.4
Homo sapiens Protein: HDAC8
Summary
InnateDB Protein IDBP-375846.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HDAC8
Protein Name histone deacetylase 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000398997
InnateDB Gene IDBG-76713 (HDAC8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 96 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 96 [view]
Protein-Protein 35 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 60 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004407 histone deacetylase activity
Biological Process
GO:0016575 histone deacetylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003084 Histone deacetylase
IPR023801 Histone deacetylase domain
PFAM PF00850
PRINTS PR01271
PIRSF PIRSF037913
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9J8F0
UniProt Splice Variant
Entrez Gene 55869
UniGene Hs.610708
RefSeq
HUGO HGNC:13315
OMIM 300269
CCDS
HPRD 02227
IMGT
EMBL AL133500 BX295542
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca