InnateDB Protein
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IDBP-376049.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SHISA5
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Protein Name
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shisa homolog 5 (Xenopus laevis)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000408223
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InnateDB Gene
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IDBG-32953 (SHISA5)
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Protein Structure
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Function |
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis. {ECO:0000269PubMed:12135983}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:12135983}; Single-pass type I membrane protein {ECO:0000269PubMed:12135983}. Nucleus membrane {ECO:0000269PubMed:12135983}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
8
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0043123
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positive regulation of I-kappaB kinase/NF-kappaB signaling
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8N114
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PhosphoSite |
PhosphoSite-Q8N114
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TrEMBL |
C9IZ46
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UniProt Splice Variant |
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Entrez Gene |
51246
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UniGene |
Hs.739088
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RefSeq |
NP_001258996
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HUGO |
HGNC:30376
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OMIM |
607290
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CCDS |
CCDS63622
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HPRD |
06290
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IMGT |
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EMBL |
AB097007
AC104448
AC134772
AF520698
AH011688
AK056328
AK075441
AK124652
AK301191
AL117413
AL832568
BC001463
CH471055
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GenPept |
AAH01463
AAM74232
AAM74235
BAB71152
BAC11623
BAC77360
BAG54061
BAH13428
CAH10587
CAH10718
EAW64885
EAW64886
EAW64887
EAW64889
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