InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: COMP

Summary

InnateDB Protein

IDBP-376143.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COMP

Protein Name

cartilage oligomeric matrix protein

Synonyms

EDM1; EPD1; MED; PSACH; THBS5;

Species

Homo sapiens

Ensembl Protein

ENSP00000403792

InnateDB Gene

IDBG-38816 (COMP)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005201	extracellular matrix structural constituent
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0030198	extracellular matrix organization

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR003367 Thrombospondin, type 3-like repeat
IPR008859 Thrombospondin, C-terminal
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR024665 Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain
IPR028974 TSP type-3 repeat

PFAM

PF00008
PF07645
PF02412
PF05735
PF11598

PRINTS

PIRSF

SMART

SM00181
SM00179

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite