Homo sapiens Protein: HOXC4
Summary
InnateDB Protein IDBP-376646.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOXC4
Protein Name homeobox C4
Synonyms cp19; HOX3; HOX3E;
Species Homo sapiens
Ensembl Protein ENSP00000399808
InnateDB Gene IDBG-37502 (HOXC4)
Protein Structure
UniProt Annotation
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0071837 HMG box domain binding
Biological Process
GO:0001501 skeletal system development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0009952 anterior/posterior pattern specification
GO:0048562 embryonic organ morphogenesis
GO:0051216 cartilage development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR017995 Homeobox protein, antennapedia type
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00025
PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-P09017
TrEMBL A0A024RB51
UniProt Splice Variant
Entrez Gene 3221
UniGene Hs.690229
RefSeq NP_705897
HUGO HGNC:5126
OMIM 142974
CCDS CCDS8873
HPRD 00860
IMGT
EMBL AC023794 AY014297 AY014298 CH471054 X07495
GenPept AAG42145 CAA30376 EAW96744 EAW96749