InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GUSB

Summary

InnateDB Protein

IDBP-376747.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GUSB

Protein Name

glucuronidase, beta

Synonyms

BG; MPS7;

Species

Homo sapiens

Ensembl Protein

ENSP00000391390

InnateDB Gene

IDBG-18414 (GUSB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004566	beta-glucuronidase activity

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006027	glycosaminoglycan catabolic process
GO:0030203	glycosaminoglycan metabolic process
GO:0030212	hyaluronan metabolic process
GO:0030214	hyaluronan catabolic process
GO:0044281	small molecule metabolic process

Cellular Component

GO:0016020	membrane
GO:0043202	lysosomal lumen
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR006103 Glycoside hydrolase, family 2, TIM barrel
IPR006104 Glycosyl hydrolases family 2, sugar binding domain
IPR008979 Galactose-binding domain-like
IPR017853 Glycoside hydrolase, superfamily

PFAM

PF02836
PF02837

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P08236

PhosphoSite