Version 5.4
Homo sapiens Protein: APOBEC3H
Summary
InnateDB Protein IDBP-377065.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOBEC3H
Protein Name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000393520
InnateDB Gene IDBG-8048 (APOBEC3H)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004126 cytidine deaminase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
Biological Process
GO:0009972 cytidine deamination
GO:0010529 negative regulation of transposition
GO:0045087 innate immune response
GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0048525 negative regulation of viral process
GO:0051607 defense response to virus
GO:0070383 DNA cytosine deamination
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002125 CMP/dCMP deaminase, zinc-binding
IPR013158 APOBEC-like, N-terminal
IPR016193 Cytidine deaminase-like
PFAM PF00383
PF08210
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NTF7
PhosphoSite PhosphoSite-Q6NTF7
TrEMBL
UniProt Splice Variant
Entrez Gene 164668
UniGene Hs.440515
RefSeq NP_001159476
HUGO HGNC:24100
OMIM 610976
CCDS CCDS54532
HPRD 16508
IMGT
EMBL AL031846 BC069023 BQ052182 CR456481 FJ376613
GenPept AAH69023 ACK77774 CAG30367

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca