Homo sapiens Protein: USP4
Summary
InnateDB Protein IDBP-377178.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP4
Protein Name ubiquitin specific peptidase 4 (proto-oncogene)
Synonyms UNP; Unph;
Species Homo sapiens
Ensembl Protein ENSP00000400623
InnateDB Gene IDBG-34595 (USP4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 102 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 102 [view]
Protein-Protein 99 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004221 ubiquitin thiolesterase activity
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0031685 adenosine receptor binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination
GO:0031397 negative regulation of protein ubiquitination
GO:0031647 regulation of protein stability
GO:0034394 protein localization to cell surface
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR006615 Peptidase C19, ubiquitin-specific peptidase, DUSP domain
IPR029071 Ubiquitin-related domain
PFAM PF06337
PRINTS
PIRSF
SMART SM00695
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13107
PhosphoSite PhosphoSite-Q13107
TrEMBL
UniProt Splice Variant
Entrez Gene 7375
UniGene Hs.77500
RefSeq NP_001238806
HUGO HGNC:12627
OMIM 603486
CCDS CCDS58832
HPRD 04598
IMGT
EMBL AC121247 AF017305 AF017306 AK291795 BC068017 BC125130 U20657
GenPept AAB72237 AAC27355 AAC27356 AAI25131 BAF84484