InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RAD23B

Summary

InnateDB Protein

IDBP-377191.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAD23B

Protein Name

RAD23 homolog B (S. cerevisiae)

Synonyms

HHR23B; HR23B; P58;

Species

Homo sapiens

Ensembl Protein

ENSP00000405623

InnateDB Gene

IDBG-79797 (RAD23B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 248 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	248 [view]
Protein-Protein	247 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003684	damaged DNA binding
GO:0003697	single-stranded DNA binding
GO:0005515	protein binding
GO:0031593	polyubiquitin binding

Biological Process

GO:0000715	nucleotide-excision repair, DNA damage recognition
GO:0000718	nucleotide-excision repair, DNA damage removal
GO:0006281	DNA repair
GO:0006289	nucleotide-excision repair
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

Cellular Component

GO:0000502	proteasome complex
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0071942	XPC complex

Protein Structure and Domains

PDB ID

InterPro

IPR000449 Ubiquitin-associated domain/translation elongation factor EF-Ts, N-terminal
IPR004806 UV excision repair protein Rad23
IPR006636 Heat shock chaperonin-binding
IPR009060 UBA-like
IPR015360 XPC-binding domain
IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote

PFAM

PF00627
PF09280

PRINTS

PR01839

PIRSF

SMART

SM00727
SM00165

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt