Version 5.4
Homo sapiens Protein: APEH
Summary
InnateDB Protein IDBP-377392.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APEH
Protein Name N-acylaminoacyl-peptide hydrolase
Synonyms AARE; ACPH; APH; D3F15S2; D3S48E; DNF15S2; OPH;
Species Homo sapiens
Ensembl Protein ENSP00000415862
InnateDB Gene IDBG-34955 (APEH)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
Experimentally validated
Total 36 [view]
Protein-Protein 34 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005737 cytoplasm
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain
IPR002925 Dienelactone hydrolase
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PF00326
PF01738
PRINTS PR00111
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JLK2
UniProt Splice Variant
Entrez Gene 327
UniGene Hs.517969
RefSeq
HUGO HGNC:586
OMIM 102645
CCDS
HPRD 00034
IMGT
EMBL AC099668
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca