Homo sapiens Protein: CSTF2
Summary
InnateDB Protein IDBP-377468.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSTF2
Protein Name cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
Synonyms CstF-64;
Species Homo sapiens
Ensembl Protein ENSP00000415705
InnateDB Gene IDBG-79279 (CSTF2)
Protein Structure
UniProt Annotation
Function One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:11598190}. Note=Localized with DDX1 in cleavage bodies.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 61 experimentally validated interaction(s) in this database.
Experimentally validated
Total 61 [view]
Protein-Protein 61 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-P33240
TrEMBL
UniProt Splice Variant
Entrez Gene 1478
UniGene Hs.623779
RefSeq
HUGO HGNC:2484
OMIM 300907
CCDS
HPRD 02652
IMGT
EMBL
GenPept