Homo sapiens Protein: GOT2
Summary
InnateDB Protein IDBP-378368.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOT2
Protein Name glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
Synonyms KAT4; KATIV; mitAAT;
Species Homo sapiens
Ensembl Protein ENSP00000394100
InnateDB Gene IDBG-34707 (GOT2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity
GO:0016212 kynurenine-oxoglutarate transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0044822 poly(A) RNA binding
GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
GO:0006094 gluconeogenesis
GO:0006103 2-oxoglutarate metabolic process
GO:0006531 aspartate metabolic process
GO:0006533 aspartate catabolic process
GO:0006536 glutamate metabolic process
GO:0008652 cellular amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0015908 fatty acid transport
GO:0019470 4-hydroxyproline catabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
GO:0045471 response to ethanol
GO:0097052 L-kynurenine metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000796 Aspartate/other aminotransferase
IPR004839 Aminotransferase, class I/classII
IPR015424 Pyridoxal phosphate-dependent transferase
PFAM PF00155
PRINTS PR00799
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P00505
PhosphoSite PhosphoSite-P00505
TrEMBL
UniProt Splice Variant
Entrez Gene 2806
UniGene Hs.657304
RefSeq NP_001273149
HUGO HGNC:4433
OMIM 138150
CCDS CCDS67045
HPRD 00684
IMGT
EMBL AC012183 AK223271 AK295993 BC000525 M22632
GenPept AAA35568 AAH00525 BAD96991 BAG58768