InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DYNC1LI2

Summary

InnateDB Protein

IDBP-378568.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DYNC1LI2

Protein Name

dynein, cytoplasmic 1, light intermediate chain 2

Synonyms

DNCLI2; LIC2;

Species

Homo sapiens

Ensembl Protein

ENSP00000394289

InnateDB Gene

IDBG-35488 (DYNC1LI2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.

Experimentally validated
Total	30 [view]
Protein-Protein	30 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003777	microtubule motor activity
GO:0005524	ATP binding

Biological Process

GO:0006810	transport
GO:0007018	microtubule-based movement
GO:0008152	metabolic process
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

Cellular Component

GO:0005813	centrosome
GO:0005829	cytosol
GO:0005868	cytoplasmic dynein complex
GO:0005874	microtubule
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR022780 Dynein family light intermediate chain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF05783

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O43237

PhosphoSite

PhosphoSite-O43237

TrEMBL

UniProt Splice Variant

Entrez Gene

1783

UniGene

Hs.644723

RefSeq

NP_001273086

HUGO

HGNC:2966

OMIM

611406

CCDS

CCDS67049

HPRD

09923

IMGT

EMBL

AC018557 AC044802 AF035812 AK291766 AK303031 BC025959 CH471092

GenPept

AAB88513 AAH25959 BAF84455 BAG64156 EAW83039