Version 5.4
Homo sapiens Protein: CHRNB4
Summary
InnateDB Protein IDBP-378653.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHRNB4
Protein Name cholinergic receptor, nicotinic, beta 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000416386
InnateDB Gene IDBG-25047 (CHRNB4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004889 acetylcholine-activated cation-selective channel activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0015276 ligand-gated ion channel activity
GO:0015464 acetylcholine receptor activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0007165 signal transduction
GO:0007268 synaptic transmission
GO:0007271 synaptic transmission, cholinergic
GO:0034220 ion transmembrane transport
GO:0046928 regulation of neurotransmitter secretion
GO:0060084 synaptic transmission involved in micturition
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR002394 Nicotinic acetylcholine receptor
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
PFAM PF02931
PRINTS PR00254
PR00252
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P30926
PhosphoSite PhosphoSite-P30926
TrEMBL
UniProt Splice Variant
Entrez Gene 1143
UniGene Hs.624178
RefSeq NP_001243496
HUGO HGNC:1964
OMIM 118509
CCDS CCDS58392
HPRD 00337
IMGT
EMBL AC022748 AC067863 AF306325 AF306326 AF306327 AF306328 AF306329 AF453877 AJ306454 AJ306455 AJ306456 AJ306457 AJ306458 AJ306459 BC096080 BC096081 BC096082 BC096083 U48861 U62439 X68275 Y08416
GenPept AAA92123 AAB40117 AAH96080 AAH96081 AAH96082 AAH96083 AAL02062 AAL57840 CAA48336 CAA69693 CAC34819

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca