InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GRM2

Summary

InnateDB Protein

IDBP-378798.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GRM2

Protein Name

glutamate receptor, metabotropic 2

Synonyms

GLUR2; GPRC1B; mGlu2; MGLUR2;

Species

Homo sapiens

Ensembl Protein

ENSP00000408906

InnateDB Gene

IDBG-37548 (GRM2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	1 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007186

G-protein coupled receptor signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000162 GPCR, family 3, metabotropic glutamate receptor
IPR000337 GPCR, family 3
IPR001458 GPCR, family 3, metabotropic glutamate receptor 2
IPR001828 Extracellular ligand-binding receptor
IPR017978 GPCR, family 3, C-terminal
IPR028082 Periplasmic binding protein-like I

PFAM

PF01094
PF00003

PRINTS

PR00593
PR00248
PR01052

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite