InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RCN1

Summary

InnateDB Protein

IDBP-37944.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RCN1

Protein Name

reticulocalbin 1, EF-hand calcium binding domain

Synonyms

HEL-S-84; PIG20; RCAL; RCN;

Species

Homo sapiens

Ensembl Protein

ENSP00000054950

InnateDB Gene

IDBG-37942 (RCN1)

Protein Structure

UniProt Annotation

Function

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.

Subcellular Localization

Endoplasmic reticulum lumen.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	55 [view]
Protein-Protein	55 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0001701	in utero embryonic development
GO:0043010	camera-type eye development

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen

Protein Structure and Domains

PDB ID

InterPro

IPR002048 EF-hand domain

PFAM

PF00036
PF13202
PF13405

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q15293

PhosphoSite

PhosphoSite-Q15293

TrEMBL

V9HW95

UniProt Splice Variant

Entrez Gene

5954

UniGene

Hs.97887

RefSeq

NP_002892

HUGO

HGNC:9934

OMIM

602735

CCDS

CCDS7876

HPRD

IMGT

EMBL

AL035078 AL049635 AL078612 AL138970 AY423728 BC010120 CH471064 D42073 FJ224346 Z95332

GenPept

AAH10120 AAS00491 ACI46038 BAA07670 EAW68227 EAW68228