Version 5.4
Homo sapiens Protein: ITIH1
Summary
InnateDB Protein IDBP-379681.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITIH1
Protein Name inter-alpha (globulin) inhibitor H1
Synonyms H1P; IATIH; IGHEP1; ITI-HC1; ITIH; SHAP;
Species Homo sapiens
Ensembl Protein ENSP00000395836
InnateDB Gene IDBG-39685 (ITIH1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0009982 pseudouridine synthase activity
Biological Process
GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification
GO:0010951 negative regulation of endopeptidase activity
GO:0030212 hyaluronan metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR010600 Inter-alpha-trypsin inhibitor heavy chain, C-terminal
IPR020103 Pseudouridine synthase, catalytic domain
PFAM PF06668
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7C0N0
UniProt Splice Variant
Entrez Gene 3697
UniGene Hs.420257
RefSeq
HUGO HGNC:6166
OMIM 147270
CCDS
HPRD 00927
IMGT
EMBL AC006254
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca