InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PLAU

Summary

InnateDB Protein

IDBP-380338.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLAU

Protein Name

plasminogen activator, urokinase

Synonyms

ATF; BDPLT5; QPD; u-PA; UPA; URK;

Species

Homo sapiens

Ensembl Protein

ENSP00000388474

InnateDB Gene

IDBG-78889 (PLAU)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	24 [view]
Protein-Protein	20 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding

Biological Process

GO:0006508

proteolysis

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000001 Kringle
IPR000742 Epidermal growth factor-like domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR013806 Kringle-like fold

PFAM

PF00051
PF00008
PF00089

PRINTS

PR00722

PIRSF

SMART

SM00130
SM00181
SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt