InnateDB Protein
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IDBP-38056.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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KLF12
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Protein Name
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Kruppel-like factor 12
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Synonyms
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AP-2rep; AP2REP;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000366894
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InnateDB Gene
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IDBG-38048 (KLF12)
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Protein Structure
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|
Function |
Confers strong transcriptional repression to the AP-2- alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
4
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
1
[view]
|
RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0000122
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negative regulation of transcription from RNA polymerase II promoter
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GO:0006351
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transcription, DNA-templated
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GO:0006357
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regulation of transcription from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
|
Modification |
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SwissProt |
Q9Y4X4
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PhosphoSite |
PhosphoSite-Q9Y4X4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
11278
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UniGene |
Hs.373857
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RefSeq |
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HUGO |
HGNC:6346
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OMIM |
607531
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CCDS |
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HPRD |
06336
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IMGT |
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EMBL |
AF113122
AF161471
AF312866
AF312867
AF312868
AF312869
AF312870
AF312871
AF312872
AJ243274
AK291397
AL138713
AL139036
AL159972
AL160032
BC019680
CH471093
HF546212
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GenPept |
AAF14863
AAF29086
AAH19680
AAK12082
BAF84086
CAB46982
CAH70670
CAH71998
CAH74171
CAI15634
CCO02798
EAW80529
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