Version 5.4
Homo sapiens Protein: DCTN1
Summary
InnateDB Protein IDBP-380566.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCTN1
Protein Name dynactin 1
Synonyms DAP-150; DP-150; P135;
Species Homo sapiens
Ensembl Protein ENSP00000416711
InnateDB Gene IDBG-57205 (DCTN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 111 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 111 [view]
Protein-Protein 111 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016740 transferase activity
GO:0045502 dynein binding
GO:0048037 cofactor binding
Biological Process
GO:0010970 microtubule-based transport
Cellular Component
GO:0005869 dynactin complex
Protein Structure and Domains
PDB ID
InterPro IPR000533 Tropomyosin
IPR000938 CAP Gly-rich domain
IPR015083 Polyketide synthase, docking domain
IPR022157 Dynein associated protein
PFAM PF00261
PF12718
PF01302
PF08990
PF12455
PRINTS PR00194
PIRSF
SMART SM01052
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6AWB1
UniProt Splice Variant
Entrez Gene 1639
UniGene Hs.740125
RefSeq
HUGO HGNC:2711
OMIM 601143
CCDS
HPRD 07206
IMGT
EMBL AC005041 BX647972
GenPept CAH10572

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca