InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IGF2BP1

Summary

InnateDB Protein

IDBP-380657.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IGF2BP1

Protein Name

insulin-like growth factor 2 mRNA binding protein 1

Synonyms

CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000389135

InnateDB Gene

IDBG-57431 (IGF2BP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 63 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	63 [view]
Protein-Protein	63 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003729	mRNA binding
GO:0003730	mRNA 3'-UTR binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding
GO:0045182	translation regulator activity
GO:0048027	mRNA 5'-UTR binding

Biological Process

GO:0010467	gene expression
GO:0010610	regulation of mRNA stability involved in response to stress
GO:0017148	negative regulation of translation
GO:0042035	regulation of cytokine biosynthetic process
GO:0051028	mRNA transport
GO:0070934	CRD-mediated mRNA stabilization

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0010494	cytoplasmic stress granule
GO:0030027	lamellipodium
GO:0030175	filopodium
GO:0030424	axon
GO:0030426	growth cone
GO:0030529	ribonucleoprotein complex
GO:0043197	dendritic spine
GO:0048471	perinuclear region of cytoplasm
GO:0070937	CRD-mediated mRNA stability complex