Version 5.4
Homo sapiens Protein: CROT
Summary
InnateDB Protein IDBP-380899.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CROT
Protein Name carnitine O-octanoyltransferase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000404867
InnateDB Gene IDBG-24917 (CROT)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0008458 carnitine O-octanoyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0009437 carnitine metabolic process
GO:0015936 coenzyme A metabolic process
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
GO:0051791 medium-chain fatty acid metabolic process
Cellular Component
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR000542 Acyltransferase ChoActase/COT/CPT
PFAM PF00755
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKG9
PhosphoSite PhosphoSite-Q9UKG9
TrEMBL
UniProt Splice Variant
Entrez Gene 54677
UniGene Hs.125039
RefSeq NP_001230674
HUGO HGNC:2366
OMIM 606090
CCDS CCDS59062
HPRD 12081
IMGT
EMBL AC005045 AF073770 AF168793 BC039004 BC051874 CH236949 CH471091
GenPept AAD41654 AAF03234 AAH39004 AAH51874 EAL24177 EAW76954

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca