InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SRI

Summary

InnateDB Protein

IDBP-381181.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SRI

Protein Name

sorcin

Synonyms

CP-22; CP22; SCN; V19;

Species

Homo sapiens

Ensembl Protein

ENSP00000391148

InnateDB Gene

IDBG-25472 (SRI)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	32 [view]
Protein-Protein	29 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004198	calcium-dependent cysteine-type endopeptidase activity
GO:0005102	receptor binding
GO:0005246	calcium channel regulator activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0044325	ion channel binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001508	action potential
GO:0006508	proteolysis
GO:0006810	transport
GO:0006880	intracellular sequestering of iron ion
GO:0006942	regulation of striated muscle contraction
GO:0007165	signal transduction
GO:0007507	heart development
GO:0007517	muscle organ development
GO:0008016	regulation of heart contraction
GO:0010459	negative regulation of heart rate
GO:0010649	regulation of cell communication by electrical coupling
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0051924	regulation of calcium ion transport
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0086004	regulation of cardiac muscle cell contraction
GO:1901077	regulation of relaxation of muscle
GO:1901841	regulation of high voltage-gated calcium channel activity
GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction

Cellular Component

GO:0005737	cytoplasm
GO:0005789	endoplasmic reticulum membrane
GO:0005829	cytosol
GO:0016020	membrane
GO:0016529	sarcoplasmic reticulum
GO:0030018	Z disc
GO:0030315	T-tubule
GO:0033017	sarcoplasmic reticulum membrane
GO:0042584	chromaffin granule membrane
GO:0070062	extracellular vesicular exosome