InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DLG2

Summary

InnateDB Protein

IDBP-381688.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DLG2

Protein Name

discs, large homolog 2 (Drosophila)

Synonyms

chapsyn-110; PPP1R58; PSD-93; PSD93;

Species

Homo sapiens

Ensembl Protein

ENSP00000393049

InnateDB Gene

IDBG-66339 (DLG2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	30 [view]
Protein-Protein	28 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004385	guanylate kinase activity
GO:0005515	protein binding

Biological Process

GO:0010923	negative regulation of phosphatase activity
GO:0046939	nucleotide phosphorylation

Cellular Component

GO:0005886	plasma membrane
GO:0014069	postsynaptic density

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00018
PF14604
PF00625
PF07653

PRINTS

PR00452

PIRSF

SMART

SM00326
SM00072

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt