Version 5.4
Homo sapiens Protein: APRT
Summary
InnateDB Protein IDBP-381777.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APRT
Protein Name adenine phosphoribosyltransferase
Synonyms AMP; APRTD;
Species Homo sapiens
Ensembl Protein ENSP00000397007
InnateDB Gene IDBG-46737 (APRT)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003999 adenine phosphoribosyltransferase activity
GO:0016208 AMP binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0009116 nucleoside metabolic process
GO:0043101 purine-containing compound salvage
GO:0044209 AMP salvage
GO:0044281 small molecule metabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000836 Phosphoribosyltransferase domain
IPR029057 Phosphoribosyltransferase-like
PFAM PF00156
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P07741
PhosphoSite PhosphoSite-P07741
TrEMBL H3BSW3
UniProt Splice Variant
Entrez Gene 353
UniGene
RefSeq NP_001025189
HUGO HGNC:626
OMIM 102600
CCDS CCDS45546
HPRD 00029
IMGT
EMBL AC092384 AY306126 BC107151 BM550173 CH471184 CR749423 M16446 Y00486
GenPept AAA51769 AAI07152 AAP45051 CAA68543 CAH18261 EAW66761

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca