InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TFG

Summary

InnateDB Protein

IDBP-381786.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TFG

Protein Name

TRK-fused gene

Synonyms

HMSNP; SPG57; TF6; TRKT3;

Species

Homo sapiens

Ensembl Protein

ENSP00000397182

InnateDB Gene

IDBG-47460 (TFG)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	47 [view]
Protein-Protein	47 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0008219	cell death
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

Cellular Component

GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000270 Phox/Bem1p

PFAM

PF00564

PRINTS

PIRSF

SMART

SM00666

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q92734

PhosphoSite

PhosphoSite-Q92734

TrEMBL

Q7Z427

UniProt Splice Variant

Entrez Gene

10342

UniGene

Hs.677942

RefSeq

XP_005247123

HUGO

HGNC:11758

OMIM

602498

CCDS

CCDS56266

HPRD

03932

IMGT

EMBL

AB097040 AC068763 AC069223 AK093456 BC001483 BC009241 BC023599 BT007428 CH471052 CR456781 X85960 Y07968

GenPept

AAH01483 AAH09241 AAH23599 AAP36096 BAC77393 BAG52721 CAA59936 CAA69264 CAG33062 EAW79813 EAW79814 EAW79815 EAW79816 EAW79817