Version 5.4
Homo sapiens Protein: WFIKKN2
Summary
InnateDB Protein IDBP-381798.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WFIKKN2
Protein Name WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000405889
InnateDB Gene IDBG-59338 (WFIKKN2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001134 Netrin domain
IPR002223 Proteinase inhibitor I2, Kunitz metazoa
IPR002350 Kazal domain
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR018933 Netrin module, non-TIMP type
PFAM PF00014
PF00050
PF07648
PF07679
PF07686
PF01759
PRINTS PR00759
PIRSF
SMART SM00131
SM00280
SM00408
SM00409
SM00643
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9J6G4
UniProt Splice Variant
Entrez Gene 124857
UniGene Hs.211475
RefSeq
HUGO HGNC:30916
OMIM 610895
CCDS
HPRD 18303
IMGT
EMBL AC091062
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca