Version 5.4
Homo sapiens Protein: TFPI2
Summary
InnateDB Protein IDBP-382019.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFPI2
Protein Name tissue factor pathway inhibitor 2
Synonyms PP5; REF1; TFPI-2;
Species Homo sapiens
Ensembl Protein ENSP00000416370
InnateDB Gene IDBG-27153 (TFPI2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002223 Proteinase inhibitor I2, Kunitz metazoa
PFAM PF00014
PRINTS PR00759
PIRSF
SMART SM00131
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7C4A3
UniProt Splice Variant
Entrez Gene 7980
UniGene Hs.732432
RefSeq
HUGO HGNC:11761
OMIM 600033
CCDS
HPRD 08962
IMGT
EMBL AC002076
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca