Version 5.4
Homo sapiens Protein: SESN3
Summary
InnateDB Protein IDBP-382281.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SESN3
Protein Name sestrin 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000407008
InnateDB Gene IDBG-68476 (SESN3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:12607115}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:1901031 regulation of response to reactive oxygen species
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR006730 Sestrin
IPR029032 AhpD-like
PFAM PF04636
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58005
PhosphoSite PhosphoSite-P58005
TrEMBL
UniProt Splice Variant
Entrez Gene 143686
UniGene Hs.739684
RefSeq
HUGO HGNC:23060
OMIM 607768
CCDS
HPRD 09682
IMGT
EMBL AC016896 AC021174 AF086251 AK096300 AK302366 AP000787 BC017296 BF328700 BG291497
GenPept AAH17296 BAC04754 BAH13685

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca