Homo sapiens Protein: DYNC1I1
Summary
InnateDB Protein IDBP-382367.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DYNC1I1
Protein Name dynein, cytoplasmic 1, intermediate chain 1
Synonyms DNCI1; DNCIC1;
Species Homo sapiens
Ensembl Protein ENSP00000398118
InnateDB Gene IDBG-27907 (DYNC1I1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 81 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 81 [view]
Protein-Protein 80 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0030507 spectrin binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0047496 vesicle transport along microtubule
Cellular Component
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0000922 spindle pole
GO:0005829 cytosol
GO:0005868 cytoplasmic dynein complex
GO:0005874 microtubule
GO:0031982 vesicle
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR025956 Cytoplasmic dynein 1 intermediate chain 1/2
PFAM PF00400
PF11540
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14576
PhosphoSite PhosphoSite-O14576
TrEMBL Q75LS9
UniProt Splice Variant
Entrez Gene 1780
UniGene Hs.603714
RefSeq NP_001265350
HUGO HGNC:2963
OMIM 603772
CCDS CCDS64718
HPRD 04798
IMGT
EMBL AC002452 AC002540 AC022261 AC091779 AF063228 AF123074 AK091339 AK297427 BC022540 CH471091
GenPept AAB67047 AAB70113 AAC33443 AAD26852 AAH22540 AAS07455 BAC03639 BAG59855 EAW76753