Version 5.4
Homo sapiens Gene: DYNC1I1
Summary
InnateDB Gene IDBG-27907.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DYNC1I1
Gene Name dynein, cytoplasmic 1, intermediate chain 1
Synonyms DNCI1; DNCIC1
Species Homo sapiens
Ensembl Gene ENSG00000158560
Encoded Proteins
IDBP-27909
dynein, cytoplasmic 1, intermediate chain 1
IDBP-27911
dynein, cytoplasmic 1, intermediate chain 1
IDBP-382366
dynein, cytoplasmic 1, intermediate chain 1
IDBP-382367
dynein, cytoplasmic 1, intermediate chain 1
IDBP-382368
dynein, cytoplasmic 1, intermediate chain 1
IDBP-382369
dynein, cytoplasmic 1, intermediate chain 1
IDBP-476192
dynein, cytoplasmic 1, intermediate chain 1
IDBP-485495
dynein, cytoplasmic 1, intermediate chain 1
IDBP-584920
dynein, cytoplasmic 1, intermediate chain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:95772506-96110071
Strand Forward strand
Band q21.3
Transcripts
ENST00000359388 ENSP00000352348
ENST00000324972 ENSP00000320130
ENST00000447467 ENSP00000392337
ENST00000437599 ENSP00000398118
ENST00000413338 ENSP00000411957
ENST00000457059 ENSP00000412444
ENST00000524053 ENSP00000428934
ENST00000518089 ENSP00000428273
ENST00000519371
ENST00000497626
ENST00000537881 ENSP00000438377
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 81 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 81 [view]
Protein-Protein 80 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0030507 spectrin binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0047496 vesicle transport along microtubule
Cellular Component
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0000922 spindle pole
GO:0005829 cytosol
GO:0005868 cytoplasmic dynein complex
GO:0005874 microtubule
GO:0031982 vesicle
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029757
View Gene Order
ENSBTAG00000027134
Not yet available
Pathways
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
REACT_121399
MHC class II antigen presentation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
KEGG
hsa04962
Vasopressin-regulated water reabsorption pathway
hsa04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt O14576
TrEMBL A4D1I7 C9J3E7 E5RFE1 E5RJ75 Q75LS9 Q75MI9
UniProt Splice Variant
Entrez Gene 1780
UniGene Hs.440364 Hs.603714
RefSeq NM_001135556 NM_001135557 NM_001278421 NM_001278422 NM_004411 XM_006715870
HUGO HGNC:2963
OMIM 603772
CCDS CCDS47645 CCDS47646 CCDS5644 CCDS64718
HPRD
IMGT
EMBL AC002452 AC002540 AC022261 AC091779 AF063228 AF123074 AK091339 AK297427 AK313148 BC022540 CH236949 CH471091
GenPept AAB67047 AAB70113 AAC33443 AAD26852 AAH22540 AAS01994 AAS07455 BAC03639 BAG35966 BAG59855 EAL24126 EAW76753 EAW76755
RNA Seq Atlas 1780

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca