InnateDB Protein
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IDBP-38242.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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LACRT
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Protein Name
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lacritin
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000257867
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InnateDB Gene
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IDBG-38240 (LACRT)
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Protein Structure
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|
Function |
Modulates secretion by lacrimal acinar cells.
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Subcellular Localization |
Secreted.
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Disease Associations |
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Tissue Specificity |
Expressed in secretory granules of many acinar cells in lacrimal gland and in scattered acinar cells of salivary glands.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
9
[view]
|
Protein-Protein |
9
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0008284
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positive regulation of cell proliferation
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GO:0019722
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calcium-mediated signaling
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GO:0033173
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calcineurin-NFAT signaling cascade
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GO:0034067
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protein localization to Golgi apparatus
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GO:0050679
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positive regulation of epithelial cell proliferation
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GO:0050731
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positive regulation of peptidyl-tyrosine phosphorylation
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GO:0051047
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positive regulation of secretion
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GO:0051281
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positive regulation of release of sequestered calcium ion into cytosol
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GO:0051533
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positive regulation of NFAT protein import into nucleus
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GO:0070075
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tear secretion
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9GZZ8
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PhosphoSite |
PhosphoSite-Q9GZZ8
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
90070
|
UniGene |
Hs.307096
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RefSeq |
NP_150593
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HUGO |
HGNC:16430
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OMIM |
607360
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CCDS |
CCDS8883
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HPRD |
06302
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IMGT |
|
EMBL |
AF238867
AY005150
BC062217
BC069317
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GenPept |
AAG32949
AAG44392
AAH62217
AAH69317
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