InnateDB Protein
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IDBP-383004.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CYP3A5
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Protein Name
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cytochrome P450, family 3, subfamily A, polypeptide 5
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Synonyms
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CP35; CYPIIIA5; P450PCN3; PCN3;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000401269
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InnateDB Gene
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IDBG-29632 (CYP3A5)
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Protein Structure
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Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
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Subcellular Localization |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001128
Cytochrome P450
IPR008072
Cytochrome P450, E-class, CYP3A
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PFAM |
PF00067
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PRINTS |
PR00385
PR01689
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P20815
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PhosphoSite |
PhosphoSite-P20815
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
1577
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UniGene |
Hs.571258
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RefSeq |
NP_001177413
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HUGO |
HGNC:2638
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OMIM |
605325
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CCDS |
CCDS55134
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HPRD |
05617
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IMGT |
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EMBL |
AC005020
AF280107
AK299002
BC033862
CH236956
CH471091
J04813
L35912
S74699
S74700
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GenPept |
AAA02993
AAB00083
AAD14157
AAD14158
AAG32288
AAH33862
AAS02016
BAH12923
EAL23868
EAW76638
EAW76642
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