InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DIXDC1

Summary

InnateDB Protein

IDBP-383072.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DIXDC1

Protein Name

DIX domain containing 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000394352

InnateDB Gene

IDBG-71136 (DIXDC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0031435	mitogen-activated protein kinase kinase kinase binding
GO:0043015	gamma-tubulin binding

Biological Process

GO:0007049	cell cycle
GO:0007165	signal transduction
GO:0021695	cerebellar cortex development
GO:0021795	cerebral cortex cell migration
GO:0021799	cerebral cortex radially oriented cell migration
GO:0021846	cell proliferation in forebrain
GO:0021869	forebrain ventricular zone progenitor cell division
GO:0030177	positive regulation of Wnt signaling pathway
GO:0030900	forebrain development
GO:0032956	regulation of actin cytoskeleton organization
GO:0043010	camera-type eye development
GO:0045665	negative regulation of neuron differentiation
GO:0046328	regulation of JNK cascade
GO:0046330	positive regulation of JNK cascade
GO:0050772	positive regulation of axonogenesis
GO:0070507	regulation of microtubule cytoskeleton organization
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0005938	cell cortex
GO:0043025	neuronal cell body
GO:0043234	protein complex
GO:0043679	axon terminus