Version 5.4
Homo sapiens Protein: GH2
Summary
InnateDB Protein IDBP-383118.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GH2
Protein Name growth hormone 2
Synonyms GH-V; GHL; GHV; hGH-V;
Species Homo sapiens
Ensembl Protein ENSP00000410618
InnateDB Gene IDBG-64119 (GH2)
Protein Structure
UniProt Annotation
Function Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Expressed in the placenta.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001400 Somatotropin hormone
IPR009079 Four-helical cytokine-like, core
PFAM PF00103
PRINTS PR00836
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P01242
PhosphoSite PhosphoSite-P01242
TrEMBL
UniProt Splice Variant
Entrez Gene 2689
UniGene Hs.406754
RefSeq NP_072050
HUGO HGNC:4262
OMIM 139240
CCDS CCDS45758
HPRD 00750
IMGT
EMBL AB451332 AB451477 AC040958 AF006060 AF006061 AK312194 BC020760 CH471109 EU421715 J03071 J03756 K00470 M38451
GenPept AAA35891 AAA52552 AAA98619 AAB59547 AAB59548 AAB71828 AAB71829 AAH20760 ABZ88719 ABZ88720 ABZ88721 ABZ88722 BAG35127 BAG70146 BAG70291 EAW94238 EAW94248 EAW94252 EAW94258

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca