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InnateDB Protein
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IDBP-383330.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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KALRN
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Protein Name
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kalirin, RhoGEF kinase
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Synonyms
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ARHGEF24; CHD5; CHDS5; DUET; DUO; HAPIP; TRAD;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000402950
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InnateDB Gene
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IDBG-53661 (KALRN)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
17
[view]
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| Protein-Protein |
17
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
1 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0005089
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Rho guanyl-nucleotide exchange factor activity
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GO:0005515
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protein binding
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| Biological Process |
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GO:0032321
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positive regulation of Rho GTPase activity
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR002017
Spectrin repeat
IPR018159
Spectrin/alpha-actinin
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| PFAM |
PF00435
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| PRINTS |
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| PIRSF |
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| SMART |
SM00150
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
H7C1X7
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| UniProt Splice Variant |
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| Entrez Gene |
8997
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| UniGene |
Hs.8004
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| RefSeq |
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| HUGO |
HGNC:4814
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| OMIM |
604605
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| CCDS |
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| HPRD |
12169
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| IMGT |
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| EMBL |
AC022336
AC069233
AC080008
AC112129
AC117401
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| GenPept |
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Version 5.4