InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PILRB

Summary

InnateDB Protein

IDBP-383457.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PILRB

Protein Name

paired immunoglobin-like type 2 receptor beta

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000415775

InnateDB Gene

IDBG-31079 (PILRB)

Protein Structure

UniProt Annotation

Function

Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity

Cellular Component

GO:0005887

integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications