InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NPAS2

Summary

InnateDB Protein

IDBP-383670.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NPAS2

Protein Name

neuronal PAS domain protein 2

Synonyms

bHLHe9; MOP4; PASD4;

Species

Homo sapiens

Ensembl Protein

ENSP00000395265

InnateDB Gene

IDBG-63633 (NPAS2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.

Experimentally validated
Total	30 [view]
Protein-Protein	29 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0004871	signal transducer activity
GO:0046983	protein dimerization activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007165	signal transduction

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000014 PAS domain
IPR001067 Nuclear translocator
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain

PFAM

PF13188
PF13426
PF00010

PRINTS

PR00785

PIRSF

SMART

SM00091
SM00353

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H7C0J4

UniProt Splice Variant

Entrez Gene

4862

UniGene

Hs.681384

RefSeq

HUGO

HGNC:7895

OMIM

603347

CCDS

HPRD

09137

IMGT

EMBL

AC016738 AC092168 AC106891

GenPept