Version 5.4
Homo sapiens Protein: IL1R2
Summary
InnateDB Protein IDBP-383827.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL1R2
Protein Name interleukin 1 receptor, type II
Synonyms CD121b; CDw121b; IL-1R-2; IL-1RT-2; IL-1RT2; IL1R2c; IL1RB;
Species Homo sapiens
Ensembl Protein ENSP00000408415
InnateDB Gene IDBG-64053 (IL1R2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004910 interleukin-1, Type II, blocking receptor activity
GO:0005515 protein binding
Biological Process
GO:0019221 cytokine-mediated signaling pathway
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor type I/II
IPR004077 Interleukin-1 receptor type II
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS PR01536
PR01539
PIRSF
SMART SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JNR0
UniProt Splice Variant
Entrez Gene 7850
UniGene Hs.25333
RefSeq
HUGO HGNC:5994
OMIM 147811
CCDS
HPRD 00995
IMGT
EMBL AC005035 AC007165
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca