InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FDXR

Summary

InnateDB Protein

IDBP-384209.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FDXR

Protein Name

ferredoxin reductase

Synonyms

ADXR;

Species

Homo sapiens

Ensembl Protein

ENSP00000416515

InnateDB Gene

IDBG-67702 (FDXR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	2 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004324	ferredoxin-NADP+ reductase activity
GO:0005515	protein binding
GO:0015039	NADPH-adrenodoxin reductase activity
GO:0016491	oxidoreductase activity
GO:0070402	NADPH binding

Biological Process

GO:0006091	generation of precursor metabolites and energy
GO:0006694	steroid biosynthetic process
GO:0008203	cholesterol metabolic process
GO:0044281	small molecule metabolic process
GO:0055114	oxidation-reduction process
GO:0070995	NADPH oxidation

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase
IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain

PFAM

PF07992

PRINTS

PR00368

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P22570