Homo sapiens Protein: CUX1
Summary
InnateDB Protein IDBP-384299.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CUX1
Protein Name cut-like homeobox 1
Synonyms CASP; CDP; CDP/Cut; CDP1; Clox; COY1; CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200; p75;
Species Homo sapiens
Ensembl Protein ENSP00000409745
InnateDB Gene IDBG-547448 (CUX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003702 RNA polymerase II transcription factor activity
GO:0016564 transcription repressor activity
GO:0030528 transcription regulator activity
GO:0030674 protein binding, bridging
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000301 retrograde transport, vesicle recycling within Golgi
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0007275 multicellular organismal development
GO:0030324 lung development
GO:0042491 auditory receptor cell differentiation
GO:0050775 positive regulation of dendrite morphogenesis
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030173 integral component of Golgi membrane
Protein Structure and Domains
PDB ID
InterPro IPR012955 CASP, C-terminal
IPR023353 LemA-like domain
PFAM PF08172
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P39880
PhosphoSite PhosphoSite-P39880
TrEMBL Q75MT4
UniProt Splice Variant
Entrez Gene 1523
UniGene Hs.707744
RefSeq NP_001189474
HUGO HGNC:2557
OMIM 116896
CCDS CCDS56499
HPRD 00295
IMGT
EMBL AC005072 AC005086 AC005088 AC005096 AC005103 AC092788 AF047825 AK122726 BC066592 M74099
GenPept AAC78778 AAH66592 AAP22331 AAS07388 AAS07406 AAS07410 AAS07523 BAG53691