Version 5.4
Homo sapiens Protein: TSEN34
Summary
InnateDB Protein IDBP-384649.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSEN34
Protein Name tRNA splicing endonuclease 34 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000397402
InnateDB Gene IDBG-68287 (TSEN34)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 14 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000213 tRNA-intron endonuclease activity
GO:0003676 nucleic acid binding
GO:0005515 protein binding
Biological Process
GO:0000379 tRNA-type intron splice site recognition and cleavage
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0000214 tRNA-intron endonuclease complex
Protein Structure and Domains
PDB ID
InterPro IPR006676 tRNA-splicing endonuclease
IPR006677 tRNA intron endonuclease, catalytic domain-like
IPR016690 tRNA-splicing endonuclease, SEN34 subunit
PFAM PF01974
PRINTS
PIRSF PIRSF017250
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E7EQB3
UniProt Splice Variant
Entrez Gene 79042
UniGene Hs.15580
RefSeq NP_001269262
HUGO HGNC:15506
OMIM 608754
CCDS CCDS74446
HPRD 10038
IMGT
EMBL AC012314
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca