Version 5.4
Homo sapiens Protein: SETD8
Summary
InnateDB Protein IDBP-384847.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SETD8
Protein Name SET domain containing (lysine methyltransferase) 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000413811
InnateDB Gene IDBG-63410 (SETD8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0018024 histone-lysine N-methyltransferase activity
Biological Process
GO:0034968 histone lysine methylation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR001214 SET domain
IPR016858 Histone H4-K20 methyltransferase
PFAM PF00856
PRINTS
PIRSF PIRSF027717
SMART SM00317
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JKQ0
UniProt Splice Variant
Entrez Gene 387893
UniGene Hs.674365
RefSeq
HUGO HGNC:29489
OMIM 607240
CCDS
HPRD 06254
IMGT
EMBL AC137767 AC145423
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca