Version 5.4
Homo sapiens Protein: GPR85
Summary
InnateDB Protein IDBP-385422.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR85
Protein Name G protein-coupled receptor 85
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000396763
InnateDB Gene IDBG-36913 (GPR85)
Protein Structure
UniProt Annotation
Function Orphan receptor.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in brain and testis. Lower levels in small intestine, placenta and spleen. In brain regions, detected in all regions tested, but somewhat lower levels in the corpus callosum, medulla and spinal cord. {ECO:0000269PubMed:10833454, ECO:0000269PubMed:10978537}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P60893
PhosphoSite PhosphoSite-P60893
TrEMBL C9JDK8
UniProt Splice Variant
Entrez Gene 54329
UniGene Hs.152009
RefSeq NP_001139739
HUGO HGNC:4536
OMIM 605188
CCDS CCDS5758
HPRD 05543
IMGT
EMBL AB040800 AB065688 AC073346 AF250237 AK312587 AL161959 CH236947 CH471070 JF810886
GenPept AAF79956 AAQ93365 AEP43753 BAA96646 BAC05911 BAG35481 CAB82307 EAL24372 EAW83476

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca