Version 5.4
Homo sapiens Gene: GPR85
Summary
InnateDB Gene IDBG-36913.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR85
Gene Name G protein-coupled receptor 85
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164604
Encoded Proteins
IDBP-36915
G protein-coupled receptor 85
IDBP-385422
G protein-coupled receptor 85
IDBP-385424
G protein-coupled receptor 85
IDBP-385426
G protein-coupled receptor 85
IDBP-385431
G protein-coupled receptor 85
IDBP-809332
G protein-coupled receptor 85
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:113078331-113087778
Strand Reverse strand
Band q31.1
Transcripts
ENST00000297146 ENSP00000297146
ENST00000424100 ENSP00000396763
ENST00000449591 ENSP00000401178
ENST00000449735 ENSP00000415699
ENST00000438062 ENSP00000416722
ENST00000487573
ENST00000610164 ENSP00000476863
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048216
View Gene Order
ENSBTAG00000032844
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.152009
RefSeq NM_001146265 NM_001146266 NM_001146267 NM_018970 XM_005250451
HUGO
OMIM
CCDS CCDS5758
HPRD 05543
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca