InnateDB Protein
|
IDBP-385424.4
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
GPR85
|
Protein Name
|
G protein-coupled receptor 85
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000401178
|
InnateDB Gene
|
IDBG-36913 (GPR85)
|
Protein Structure
|
|
Function |
Orphan receptor.
|
Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
Highly expressed in brain and testis. Lower levels in small intestine, placenta and spleen. In brain regions, detected in all regions tested, but somewhat lower levels in the corpus callosum, medulla and spinal cord. {ECO:0000269PubMed:10833454, ECO:0000269PubMed:10978537}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
Accession |
GO Term |
GO:0004930
|
G-protein coupled receptor activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like
IPR017452
GPCR, rhodopsin-like, 7TM
|
PFAM |
PF00001
|
PRINTS |
PR00237
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P60893
|
PhosphoSite |
PhosphoSite-P60893
|
TrEMBL |
C9JDK8
|
UniProt Splice Variant |
|
Entrez Gene |
54329
|
UniGene |
Hs.152009
|
RefSeq |
NP_001139738
|
HUGO |
HGNC:4536
|
OMIM |
605188
|
CCDS |
CCDS5758
|
HPRD |
05543
|
IMGT |
|
EMBL |
AB040800
AB065688
AC073346
AF250237
AK312587
AL161959
CH236947
CH471070
JF810886
|
GenPept |
AAF79956
AAQ93365
AEP43753
BAA96646
BAC05911
BAG35481
CAB82307
EAL24372
EAW83476
|
|
|