Version 5.4
Homo sapiens Protein: AKR1B1
Summary
InnateDB Protein IDBP-386440.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKR1B1
Protein Name aldo-keto reductase family 1, member B1 (aldose reductase)
Synonyms ADR; ALDR1; ALR2; AR;
Species Homo sapiens
Ensembl Protein ENSP00000414399
InnateDB Gene IDBG-42170 (AKR1B1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 11 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR020471 Aldo/keto reductase subgroup
IPR023210 NADP-dependent oxidoreductase domain
PFAM PF00248
PRINTS PR00069
PIRSF PIRSF000097
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q59EL5
UniProt Splice Variant
Entrez Gene 231
UniGene Hs.602524
RefSeq
HUGO HGNC:381
OMIM 103880
CCDS
HPRD 00071
IMGT
EMBL AB209796 AC078847 U72619
GenPept AAB61992 BAD93033

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca