InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GPD2

Summary

InnateDB Protein

IDBP-386718.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPD2

Protein Name

glycerol-3-phosphate dehydrogenase 2 (mitochondrial)

Synonyms

GDH2; GPDM; mGPDH;

Species

Homo sapiens

Ensembl Protein

ENSP00000409708

InnateDB Gene

IDBG-72772 (GPD2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004368	glycerol-3-phosphate dehydrogenase activity
GO:0005509	calcium ion binding
GO:0016491	oxidoreductase activity
GO:0052591	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Biological Process

GO:0019563	glycerol catabolic process
GO:0044255	cellular lipid metabolic process
GO:0044281	small molecule metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005743	mitochondrial inner membrane
GO:0009331	glycerol-3-phosphate dehydrogenase complex

Protein Structure and Domains

PDB ID

InterPro

IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase
IPR002048 EF-hand domain
IPR003953 FAD binding domain
IPR006076 FAD dependent oxidoreductase

PFAM

PF00036
PF13202
PF13405
PF00890
PF01266

PRINTS

PR01001

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt