Version 5.4
Homo sapiens Protein: TFRC
Summary
InnateDB Protein IDBP-387025.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFRC
Protein Name transferrin receptor (p90, CD71)
Synonyms CD71; p90; T9; TFR; TFR1; TR; TRFR;
Species Homo sapiens
Ensembl Protein ENSP00000390133
InnateDB Gene IDBG-71016 (TFRC)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 73 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 73 [view]
Protein-Protein 71 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR003137 Protease-associated domain, PA
IPR007365 Transferrin receptor-like, dimerisation domain
IPR007484 Peptidase M28
PFAM PF02225
PF04253
PF04389
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3V0E5
UniProt Splice Variant
Entrez Gene 7037
UniGene Hs.685419
RefSeq
HUGO HGNC:11763
OMIM 190010
CCDS
HPRD 01812
IMGT
EMBL AC024937 CH471191
GenPept EAW53672

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca