InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: TFRC

Summary

InnateDB Gene

IDBG-71016.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TFRC

Gene Name

transferrin receptor (p90, CD71)

Synonyms

CD71; p90; T9; TFR; TFR1; TR; TRFR

Species

Homo sapiens

Ensembl Gene

ENSG00000072274

Encoded Proteins

IDBP-71018

transferrin receptor (p90, CD71)

IDBP-245743

transferrin receptor (p90, CD71)

IDBP-387022

transferrin receptor (p90, CD71)

IDBP-387025

transferrin receptor (p90, CD71)

IDBP-387026

transferrin receptor (p90, CD71)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:196027183-196082189

Strand

Reverse strand

Band

q29

Transcripts

ENST00000360110	ENSP00000353224
ENST00000392396	ENSP00000376197
ENST00000426789	ENSP00000414015
ENST00000420415	ENSP00000390133
ENST00000421258	ENSP00000402839
ENST00000463047
ENST00000475593
ENST00000483983
ENST00000463356
ENST00000482479
ENST00000465288
ENST00000477148
ENST00000464368
ENST00000491658
ENST00000464011

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 73 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	73 [view]
Protein-Protein	71 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003725	double-stranded RNA binding
GO:0004998	transferrin receptor activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0042802	identical protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006508	proteolysis
GO:0006879	cellular iron ion homeostasis
GO:0006898	receptor-mediated endocytosis
GO:0016032	viral process
GO:0030316	osteoclast differentiation
GO:0033572	transferrin transport
GO:0045780	positive regulation of bone resorption
GO:0055085	transmembrane transport
GO:0097286	iron ion import

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005768	endosome
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0005905	coated pit
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0042470	melanosome
GO:0043231	intracellular membrane-bounded organelle
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle